Studies on The Enhanced Biological Applications of PVA Loaded Nanocurcumin

J Annaraj, R Dhivya, M Vigneshwar, K Dharaniyambigai, G Kumaresan, M Rajasekaran

Abstract


The Yellow Asian herb turmeric has been traditionally used for centuries by Ayurvedic and medicine. Curcumin is the most powerful active anti-inflammatory, anti-cancer, anti-tumor, anti-microbial, anti-viral compound within turmeric. Curcumin has been shown to be a powerful suppressor of chronic inflammation-mediated disease processes. PVA loaded curcumin is highly potent, nontoxic. The antimicrobial properties as demonstrated in Both Gram positive and Gram negative bacteria and anti-cancer properties were studied on Gastric cancer cell lines (AGS).

Transmission electron microscopy confirms an even size distribution of PVA loaded curcumin nanoparticles in the range of 50 nm. PVA loaded curcumin freely soluble in water unlike bulk curcumin. Its activity against gastric cancer cells also has been investigated.


Keywords


Curcumin, PVA, Nanoparticle, Antimicrobial activity, Anticancer activity.

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